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Principal Scientist, Disease Genetics
Johnson & Johnson
| Janssen Research & Development, L.L.C., a Johnson & Johnson company, is recruiting for a Principal Scientist, Disease Genetics, in our Population Analytics group, to be located at our Spring House, Pennsylvania campus in the United States. The mission of the Population Analytics team is to support longitudinal, population-based studies to increase understanding and facilitate the search for therapies that prevent, intercept or cure disease. They will be responsible for integration, analysis and interpretation of data from diverse cohorts and across geographical/time scales. They will decipher causal factors such as genes, the environment and an individual’s lifestyle that will facilitate the discovery of novel targets, biomarkers and pathways implicated in disease. We expect these researchers to address with the goal of using biomedical data to build a best-in-class target identification and validation engine (TIDVALE) to feed our pipeline. Role & responsibilities: • Provide human biology/genetics expertise to partners within and outside of Janssen, analyze and interpret data from longitudinal, population and/or targeted cohort-based studies that consider individual variability in genes, environment and lifestyle, and leverage the knowledge gained to increase understanding of disease. • Provide scientific support and leadership for hypothesis generation, experimental design, and data analysis in partnership with Janssen researchers. He/she will work with a team responsible for applying statistical/machine learning methods to translate findings from analysis of population cohorts such as the UK Biobank and other orthogonal data sets to support functional, biological and pharmacological validation. • Develop machine learning and predictive modeling approaches to integrate and analyze a variety of data types (eg. demographics, clinical information from electronic health records, imaging/biosensor, WES, WGS, and other -omics data); apply approaches to address questions of interest in our therapeutic areas and facilitate interactions between colleagues across the organization. • He/she will supervise, guide and mentor junior scientists and postdoctoral fellows and in general act as an expert scientific leader to support and nurture collaborations with internal and external partners to build our TIDVALE. • Perform and publish high-quality research relevant to the mission of the organization; effectively communicate data and results to our stakeholders within and outside of J&J and work effectively with colleagues across J&J sectors.
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A M.D. and/or Ph.D. in computational sciences, biomedical sciences, statistics/biostatistics, or statistical genetics/genetic epidemiology is required. Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability. To be considered for positions with Johnson & Johnson, please follow the below steps:
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