Statistical Geneticist, Investigator

We are seeking an innovative and productive statistical geneticist, with a track record of high quality human genetic analysis.  The candidate should be comfortable applying state of the art analysis methods, and also interpreting findings in the context of the growing body of functional evidence (e.g. eQTL) to determine potential causal mechanisms.

GSK aims to improve the number of successful late stage clinical trials for innovative medicines, by both identifying and advancing drug targets that have strong evidence of a causal role in disease biology.  The Human Genetics team leverages major scientific and technological advances, including investment in biobanks linked to large-scale human health databases, cutting-edge informatics platforms, breakthrough understanding of biological pathways, functional genomics capabilities built upon rapid progress in gene editing, and leading industry-academia partnerships, in order to identify the best targets and to continue evaluation of targets through their life in the pipeline.

The successful candidate will work in a multidisciplinary, collaborative and scientifically driven environment, interacting with key academic collaborators and GSK scientists to advance drug discovery and clinical development in multiple disease areas.  This field-leading research addresses important drug discovery and development challenges, directly impacts GSK’s R&D pipeline, and publishes results in top scientific journals.

The selected Statistical Genetics Investigator(s) will:

• Develop and implement approaches to acquire, analyze, interpret and apply human genetic evidence to inform target selection and validation decisions across a range of disease areas.
• Participate in project teams with GSK scientists and external collaborators.
• Find creative solutions and quickly prototype applications to address challenging scientific questions.
• Contribute to the developing science of drug target identification and validation, providing scientific expertise within Human Genetics and across the Research organization.

Multiple Locations: Collegeville, Pennsylvania; Stevenage, United Kingdom